ISSN 1662-4009 (online)

ey0019.10-8 | New paradigms | ESPEYB19

10.8. Insulin is expressed by enteroendocrine cells during human fetal development

A Egozi , D Llivichuzhca-Loja , BT McCourt , K Bahar Halpern , L Farack , X An , F Wang , K Chen , L Konnikova , S Itzkovitz

Nat Med. 2021 Dec;27(12):2104-2107. https://pubmed.ncbi.nlm.nih.gov/34887578/Brief Summary: This study used single-cell transcriptomic analyses to generate a cell atlas of the human fetal and neonatal small intestine. Notably, the authors identified a subset of fetal enteroendocrine K/L cells (named FIKL) that express high levels of insulin and other beta cell genes.T...